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In surveys conducted by academic researchers and pharmaceutical companies, it has been revealed that constipation is a condition that’s estimated to afflict anywhere from 5 to 15% of the general population. The high incidence suggests not only that there exists a very large market for people interested in constipation treatments, but also that in response to the demand a plethora of agents have been developed to combat constipation.

The fact that there are many supplements and medications targeted toward the constipation patient might discourage new entrants into the market, however the truth is that there are fairly few (if any) universally effective treatments. Instead, the product market is fragmented into sectors, none of which can provide complete relief to the average sufferer. The market for constipation treatments can continue to support novel agents, as long as they provide new benefits over existing treatments.

Currently, the treatment market can be divided into 4 types. There are supplemental agents, which don’t require FDA approval. There are herbal agents, which usually fall outside FDA jurisdiction but has occasionally experienced periods of regulation. There are general laxative agents that are either over-the-counter or by prescription. There are the new “targeted therapies” that attempt to address molecular and hormonal causes of constipation.

The market for nutrient supplements is dominated by players such as Metamucil. The nutrients are derived from natural foods or grains that have lots of fiber. To take as an example, Metamucil comes in a powdered drink form which contains ground psyllium seeds that are extremely rich in fiber. People who take it simply mix it with fluids and drink it for a powerful daily dose.

By and large, herbal supplements are synonymous with senna, which are rich in sennosides, a class of compounds that stimulates the intestine. The constipation treatment market used to be much more crowded with other herbal supplements like aloe and cascara, but the FDA has since then cracked down on new entrants to the field because of safety concerns. Some manufacturers still produce aloe-based herbal supplements in concordance with the law.

The largest class of laxatives in the market of constipation treatments is the one that includes OTC agents found in pharmacies and apothecaries. Such laxatives come in various brand names, have various active ingredients and act in different ways. Patients might consider trying two or three classes before settling on any one. For example, lubricant laxatives help reduce water uptake by coating food in an oily cover. If a patient doesn’t respond to it, he or she might try a stimulant laxative that causes the gastrointestinal tract to contract more often for speeding up movement of contents.

The last class of medications is the one to which Amitiza belongs, new molecular therapies that are designed specifically for constipation. Amitiza for example has been approved for both IBS-C and chronic constipation. It acts by binding to a cellular molecule known as a ClC2 channel. There are a number of similar therapies being developed. Some like Amitiza promise to open up new vistas by treating constipation in entirely different ways from traditional medications.

Come to our site on treating constipation to find out the most latest ideas. Study more about osmotic laxatives by directly reading our site.

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• Types of Constipation (healthhype.com)

Many people who have read about treatments of constipation have in high likelihood learned about prunes. The prune is often thought of as a good laxative, largely because of the high proportion of dietary fiber by weight. The thing that most people don\’t realize is that prune juice alone is an excellent laxative.

The cultivation and exploitation of plums has gone on for hundreds or even thousands of years, according to the best archaeological evidence. Modern prune makers follow an ancient tradition. Plums are plucked and collected in one area where temperature is raised to about 200 degrees Fahrenheit. In ancient times this was likely done in or near an oven. After drying, the prunes can be further processed to create related products.

It\’s understood that high fiber helps give prunes its laxative properties for treating constipation. The average amount of fiber in a prune is almost 6% by weight. But there is little or no fiber in prune juice so how can the juice form be of benefit? It turns out that the other major component in prunes which gives it anti-constipation properties is the sugar sorbitol.

Sorbitol is present at almost 15% by weight of prunes, and 6% by weight of prune juice. It\’s a complex, polymeric sugar. That means on the molecular scale, it\’s a very long chain of sugars. This property allows it to absorb and retain water in the gut as it passes through. In fact, it sometimes is used as a sugar substitute in foods that are labeled \”sugar free\”.

The pear is another food that is high in sorbitol. If you\’ve chewed sugar free gum in the past, you might have noticed that a key ingredient is sorbitol. Unlike glucose, sorbitol isn\’t processed and taken in as energy. Couple that with its slightly sweet taste means that it\’s the perfect sugar substitute.

What gives sorbitol its powerful anti-constipation effects? Two things that we have mentioned are responsible: the fact that sorbitol goes through the gut without being digested and the fact that sorbitol has a tendency to retain a lot of water in the intestine. Together, this means that foods with sorbitol will become bulky with fluids.

The increased water content means that the colonic contents become softer and bulkier. A number of other constipation treatments have similar effects, two classes of which are known by their names osmotic and bulk laxatives. The benefits of prune juice are not restricted to helping stomach contents move faster, but also include important vitamins and sugars for energy. For a simple, natural food, it seems that prunes have many benefits.

The writings supplied for relieving constipation will be useful to many. Readers wanting to know more can browse over to learn about home remedies for constipation.